Frontiers Glycine and N acetylcysteine supplementation, with or without exercise, in brain health and functional aging: implications for sarcopenia and frailty in older adults GlyNAC looked like one of the most promising anti aging supplementsbut it probably isn't for most people. GlyNAC combines glycine and N acetylcysteine to provide two of the three building blocks needed to GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging The Glutathione Vs NAC: Which is Best for Skin?